Nancy Azcona attended Suffolk County Community College from 2012 to 2014, where she majored in Radio and Television. She transferred to Emerson College in Boston, Massachusetts and graduated in 2016 in TV Production. Between college graduation and her joining the Smosh staff, she held a variety of executive and assistant positions at various companies, including producer assistant at NBC News, production assistant at Vin Di Bona Productions, development coordinator at Authentic Entertainment, event coordinator and writer for FunknVibe, and executive assistant at Magical Elves, Inc.
Outside of Smosh, Nancy has been involved as an executive assistant Nailed It! Holiday!, Nailed It! Mexico, and Project Runway as an executive assistant in 2018 and 2019. She worked in the production staff for two episodes of America's Funniest Home Videos and worked as an assistant director in the 2017 short film The Beast With a Thousand Faces.