Jessie Kane Gill was born in Cleveland, Ohio and studied at the New York University Tisch School of the Arts. Outside of her appearances on Smosh, Jessie has appeared in several short films and television movies, including Midnight Racer (2017), uberPOOL (2017), Offing (2018), Thirst (2019; for which she was also a casting associate), and The Pointe (2019); as well as an active scene in theater. She also voices a minor character named Nina, as well as other various characters, in the Pokémon anime.
|2018||EVERY TRICK-OR-TREAT EVER||Every Blank Ever||Halloween Store job interviewee, Resident with candy|
|EVERY AUTUMN EVER||Office employee, Seasonal soup kitchen volunteer|
|EVERY HIGH SCHOOL RELATIONSHIP EVER||Maddy|
|GUY FLAWLESS (Dude Perfect Parody)||Totally True Documentary||Doctor|
|2019||Courtney Makes Ian & Damien Go To Therapy||Sketch||Dr. Dilf|
|Every Spa Ever||Every Blank Ever||Masseuse, Nail salon employee, Sauna-goer|
- According to her website, she plays the ukelele, cello, and autoharp, and is fluent in American Sign Language.